Commonwealth Consolidated Regulations

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RESEARCH INVOLVING HUMAN EMBRYOS REGULATIONS 2017 - REG 7E

Definition of germinal vesicle transfer

    Germinal vesicle transfer is a technique that involves taking the following steps, without intentionally modifying any nuclear DNA or mitochondrial DNA:

  (a)   removing the germinal vesicle from a maturing human egg ( egg A ) of a woman;

  (b)   removing the germinal vesicle from a maturing human egg ( egg B ) of a different woman;

  (c)   implanting the germinal vesicle removed from egg A into egg B, while seeking to minimise carryover of mitochondria from egg A to egg B;

  (d)   maturing egg B in vitro to the stage ready for fertilisation;

  (e)   fertilising egg B with a human sperm to create a zygote.



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